How we tested products. arthropods? -Prosthetic heart valve, Pathophysiology Chapter 12: Disorders of Hemo, PrepU Patho Ch. If I have children, do they need to be tested? -Hyperestrogenic state, A 40-year-old patient has been admitted to the cardiac intensive care unit after having an anterior wall myocardial infarction (MI). Avoid pain medication. -administer vitamin K STAT. Continue with Recommended Cookies. If your factor V Leiden requires you to take anticoagulant medication, here are some steps that might help you prevent injury and avoid excessive bleeding: Avoid playing contact sports or engaging in other activities that could result in physical injury. People who have inherited factor V Leiden from only one parent have a 5 percent chance of developing an abnormal blood clot by age 65. WebYour treatment may include a medicine (called a blood thinner) that prevents blood clots. Proaccelerin is a protein that is made up in the liver. WebMedicines help treat and prevent blood clots in people who are high risk for them. The nurse is planning care for a 70-year-old client who has lived with severe hemophilia since childhood. Select all that apply. Some people have a genetic mutation of the protein which is called factor V Leiden. Last updated on Aug 23, 2022. Despite this, testing for thrombophilias in women at high risk of VTE is controversial and thus hormonal contraception is generally not recommended for these women. We didn't think for one moment there was a reason to be concerned. Since vitamin K1 is so abundant in leafy green vegetables, most people dont need to worry about becoming deficient or taking a supplement. Select the most likely cause. Copyright 2000-2018 by ClotCare. ; Disseminated intravascular coagulation (DIC) also causes Factor V deficiency or Owrens disease. Is an uncertain result possible, and what would that mean? Avoid pain medication. There is no specific "diet" for people with factor V Leiden, but there are foods that can help keep your blood and body healthy, which may reduce your risk of developing a blood clot. Another cause of Factor V deficiency or Owrens disease is secondary fibrinolysis, which is a disorder which is characterized by the inability of fibrin clots to break down. Avoid constant electronic fetal monitoring. Activated protein C (APC) resistance represents the most common cause of inherited venous thrombosis.2 FVL, in turn, is the most common cause of APC resistance, accounting for 95% of such disorders.3 It is an autosomal dominant genetic disorder characterized by a mutation at one of the factor V cleavage sites, making it Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. People with factor V Leiden thrombophilia have a higher than average risk of developing a type of blood clot called a deep venous thrombosis (DVT). Good Foods. What does the light do to the bilirubin? The practitioner carefully monitors his client who exhibits hemoglobin S (HbS) genes. One of the rarest hematological diseases this article will be devoted to is Factor V deficiency or Owrens Disease. WebFactor V Leiden is the name of a specific gene mutation that results in thrombophilia, which is an increased tendency to form abnormal blood clots that can block blood vessels. 2. I am taking warfarin (brand name Coumadin) for a blood clot in my leg (DVT). However, there are certain lifestyle changes one can make to reduce the risk of abnormal clot formation. Having 2 Factor V Leiden genes (homozygous type) makes the risk much greater. Genetic Disorders : List of Different types of Genetic Disorders, What is Acid Lipase Disease or Lysosomal Acid Lipase Deficiency: Types, Causes, Symptoms, Treatment, What is Beckers Myotonia, Know its Causes, Symptoms, Treatment, Pathophysiology, Complications, Risk Factors, Dietary Dos and Donts for Migraine Sufferers, Shirshasana (Headstand) Versus Inversion Therapy Using Inversion Table, Understanding Joint Pain and Tips to Get Relief Using Home Remedies, Erectile Dysfunction: Does Opioid Cause ED, Libido: Opioid Induced Female Sexual Dysfunction. This article does not provide medical advice. Factor V Leiden is an abnormal form of Factor V, it works perfectly in the clotting pathway and speeds up clotting as expected, but it cannot be turned off easily. As the troops prepared to roll out, David abruptly collapsed and died. The best response would be: The nurse is caring for a client diagnosed with sickle cell disease. Regular noncontact exercise, such as walking or swimming, is still recommended for Which lab result would the practitioner expect to see? The best ways to avoid a c-section: 1. Having venous thrombosis in unusual sites in the body such as the brain or the liver. Most people with factor V Leiden never develop abnormal clots. -Arthritis Overview. A nurse working in an ambulatory care unit is working with a patient who has recently been diagnosed with a V Leiden mutation. The feedback link Was this Article Helpful on this page can be used to report content that is not accurate, up-to-date or questionable in any manner. -Agglutination, A client with an apparent clotting disorder is admitted to hospital. If you would like to change your settings or withdraw consent at any time, the link to do so is in our privacy policy accessible from our home page.. However, the incidence of recurrent VTE for heterozygous factor V Leiden mutation (FVL) is not significantly different from non-carriers. Webbe turned off. Having three or more risk factors for DVT may put someone at risk and could lead to a potentially fatal PE. Having venous thrombosis in unusual sites in the body such as the brain or the liver. Figuring out the best products is an extremely difficult task for buyers, and it gets even more difficult when the product is technology related. As the national patient advocate for the Coalition to Prevent DVT, Melanie helped to lead awareness efforts in March 2005 which culminated in a national media campaign that reached millions of Americans across the country, and a Senate resolution sponsored by Senator Arlen Specter (R-PA) and Senator Byron Dorgan (D-ND) officially declaring DVT Awareness Month. http://www.clotcare.com/clotcare/canceranddvt.aspx, FAQs About Warfarin (brand name Coumadin) The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The Coalition to Prevent Deep-Vein Thrombosis (DVT) This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. -Elevated congugated bilirubin Having recurring DVT or PE. The nurse determines further teaching is necessary when the mother states: When planning the client's care, the nurse should include what action? A healthy lifestyle also can lower your risk of a blood clot. Moreover, the risk of fatal bleeding during pregnancy from prophylactic anticoagulation therapy (treatment to prevent blood clots) is likely greater than the risk of death due to blood clots. An example of data being processed may be a unique identifier stored in a cookie. "My hope is that in telling David's and my story I can help raise public awareness and support health education measures surrounding this silent, insidious killer that took my husbands life - and that also affects two million Americans and takes hundreds of thousands of lives each year.". during routine pregnancy screening. 30 caps first thing in morning on empty stomach. Discussion. If an underlying Factor V deficiency or Owrens disease is not treated, it can cause various complications. Factor V is a protein that acts as a catalyst. What root cause likely underlies the client's increased risk for hemorrhage? How we tested products. Those diseases that only affect the most important liquid in the human beings which is blood, are called hematological diseases. Introduction: Factor V Leiden mutation and prothrombin G20210A mutation are the most common causes of an inherited thrombophilia and together account for 50 to 60 percent of diagnoses. This disease is either inherited from both of the parents in an autosomal recessive fashion or acquired by a person after its birth. This posting explains deep vein thrombosis (DVT) and pulmonary embolism (PE). No special lifestyle changes have to be made by people who suffer from Factor V deficiency or Owrens disease. Medical Videos Privacy Policy, Images and Text Policy Editorial Policy, Information Policy Advertising Policy, Financial Disclosure Policy Cookie Policy, About Us Contact Us. Here, we have compiled a list of the top 10 factor v leiden supplement to avoid to help you find the right products. Kemmeren JM, Algra A, Grobbee DE. The best ways to avoid a c-section: 1. You can learn more about the Coalition to Prevent Deep-Vein Thrombosis, of which ClotCare is a member, and the 2006 DVT Awareness Month at http://www.clotcare.com/clotcare/deepveinthrombosisawareness06.aspx. The consent submitted will only be used for data processing originating from this website. Factor V Deficiency can occur in the people of any race and/or gender. But it wasn't a landmine, bombing, bullet or an ambush that took her husband's life. If you have the factor V Leiden mutation, you are at greater risk of developing blood clots. Vitamin K1 deficiency causes symptoms associated with lack of blood clotting, like easy bruising, bloody nose, excessive bleeding, and heavy periods. Introduction: The incidence of factor V Leiden is documented to be around 5% in Caucasian population and is a known risk factor for venous thromboembolism (VTE). Terms of use. during routine pregnancy screening. Back side of the bracelet plate features engraving: SEE WALLET CARD. If you have been diagnosed with Factor V Leiden, you should alter your diet to prevent excessive blood clotting. Will the pain in my leg ever go away? The client is at risk for: -Cardiovascular disease, The nurse reviews the lab results of a client who has a thrombocyte count of 60 103/L (60 109/L). WebFactor V (factor 5) is one of several special proteins in your blood that help it clot. -Vessel spasm We follow a strict editorial policy and we have a zero-tolerance policy regarding any level of plagiarism. But in people who do, these abnormal clots can lead to long-term Factor V Leiden This results from a genetic change that increases the risk of blood clots, especially in deep veins. This will depend on lots of other factors including a past medical history of clots or a family history of blood clots. Long periods of sitting. That food includes the following: Sadly, there is no special way one can prevent getting this illness. -V Leiden mutation. How experienced is the lab at performing this test? There are also symptoms of severe Factor V deficiency or Owrens disease that include: A pregnant mother that suffers from Factor V deficiency or Owrens disease usually does not have any problems during pregnancy. We comply with the HONcode standard for trustworthy health information. -It converts the bilirubin into a soluble form that is easily excreted in the stool and urine. The symptoms of Factor V deficiency or Owrens disease are usually very mild. As always, you are welcome to contact Marie Walker at webmaster@clotcare.com if you still have questions. If you have the heterozygous form of factor V Leiden, the lifetime risk of developing a DVT is 10% or less, but may be higher if you have close family members who have had a DVT. Whispering into his phone, he complained about leg cramps. http://www.clotcare.com/clotcare/faq_dvtgoaway.aspx, I am taking warfarin (brand name Coumadin) for a blood clot in my leg (DVT). Which of the following supplements will the provider recommend to the client? Avoid dehydration. Medically reviewed by Drugs.com. Talk with your doctor about whether other people in your family should be tested for the faulty gene. Both men and women can have factor V Leiden. It is a medical condition that is known to cause small blood clots and also excessive bleeding, which happens due to overly active Melanie realized that people were listening and becoming more aware of DVT. The final diagnosis of Factor V deficiency or Owrens disease is made through Factor V Assay. -Warm-reacting antibodies WebHaving 1 Factor V Leiden gene (heterozygous type) slightly increases the chance of developing a blood clot. WebFactor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. These precautions might include: Some precautions to help reduce your risk of blood clots include: If your factor V Leiden requires you to take anticoagulant medication, here are some steps that might help you prevent injury and avoid excessive bleeding: Your doctor may refer you to a specialist in genetic disorders (geneticist) or a specialist in blood disorders (hematologist) for testing to determine whether the cause of your blood clots is genetic and, specifically, whether you have factor V Leiden. Thrombotic risk during oral contraceptive use and pregnancy in women with factor V Leiden or prothrombin mutation: a rational approach to contraception. US Medical Eligibility Criteria for Contraceptive Use, 2010. WebFactor V (factor 5) is one of several special proteins in your blood that help it clot. WebFactor V is one of the proteins needed to make blood form clots. Activated protein C (APC) resistance represents the most common cause of inherited venous thrombosis.2 FVL, in turn, is the most common cause of APC resistance, accounting for 95% of such disorders.3 It is an autosomal dominant genetic disorder characterized by a mutation at one of the factor V cleavage sites, making it In general, you should avoid: Smoking, vaping and tobacco use. -Administration of vitamin K injections as ordered. Thrombin is the main activator and turns fibrinogen into fibrin. Failure of clot retraction is indicative of what? On the basis of these data, in women with coronary disease, the estimated number needed to screen for factor V Leiden to avoid an HRT-associated VTE during 5 years of treatment is 376. One Factor V Leiden gene and one normal gene (heterozygote) Two Factor V Leiden genes (homozygote) Approximately 1 in 25 people will inherit one factor V Leiden gene and fewer than 1 in 1000 people will inherit 2. Spontaneous post-surgery autoimmune reactions. Drinking too much alcohol, or Factor V deficiency or Owrens disease is so rare that is has been estimated that it will affect only one person per million people. How we tested products. -Polycythemia As the national patient advocate for the Coalition to Prevent DVT, Melanie helped to lead awareness efforts in March 2005 which culminated in a national media campaign that Is there anything else I should do to protect my self against getting blood clots? A nurse is caring for a client diagnosed with immune thrombocytopenic purpura (ITP). -Absence of factor Xa ABSTRACT: Factor V Leiden thrombophilia is a genetic disorder that may increase a patients risk of developing a venous thromboembolism (VTE). Overview. Web-Factor V gene mutation A 40-year-old patient has been admitted to the cardiac intensive care unit after having an anterior wall myocardial infarction (MI). His health record reveals that he has been treated for complications of chronic alcoholism for the past 10 years. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It increases the chances that your blood will form abnormal blood clots that can be dangerous. It is estimated that the risk of VTE increases 3 to 5 times in individuals using second-generation COCs and up to 6 to 8 times in those using third-generation COCs. Women taking COCs have, as with any other hormonal contraception, an increased risk of venous thromboembolism (VTE). Available for Android and iOS devices. Women who carry the factor V Leiden mutation may have an increased tendency to develop blood clots during pregnancy or when taking the hormone estrogen. 2018;43 (5) (Specialty&Oncology suppl):12-15. US Pharm. Through the action of actin and myosin, filaments in platelets contribute to clot retraction. Which of the nurse's explanations best characterizes DIC? -prescribe a trial of desmopressin acetate (DDAVP) to rule out von Willebrand disease. ", - "I must stop breast-feeding my baby because of the anemia. Factor V Leiden is caused by a faulty gene that you inherit from one or both parents. nutritional supplements, and natural therapies will not alter ones genetic make-up. Which of the following medications does the nurse anticipate administering to treat this disorder? WebFactor V Leiden is the most common inherited condition causing increased blood clotting. Since receiving that call, Melanie has become more aware of deep-vein thrombosis (DVT) and pulmonary embolism (PE). This posting explains the PT-INR test, which is the test used to measure how well warfarin is working. The disorder is most common in people who are white and of European descent. Discussion. About 1 of every 250 Black people in America has the prothrombin gene mutation. Will the pain in my leg ever go away? Risk factors for venous thromboembolism. Current management strategies involve the use of pharmacotherapy, when indicated, in the event of deep venous thrombosis or The nurse is reviewing modifiable risk factors with the patient to avoid the redevelopment of thromboembolic complications, possibly leading to a second MI. -assess the child for signs and symptoms of hemophilia A. These conditions include multiple risk factors for cardiovascular disease, hypertension, history of high blood pressure during pregnancy, superficial venous thrombosis, ischemic heart disease, stroke, hyperlipidemia, and valvular heart disease. Due to the replacement of normal bone marrow with malignant cells, the nurse teaches the client to prevent scratches, scrapes, and cuts. If your factor V Leiden requires you to take anticoagulant medication, here are some steps that might help you prevent injury and avoid excessive bleeding: Avoid playing contact sports or engaging in other activities that could result in physical injury. The practitioner know that the client is predisposed to life-threatening infection due to damage by HbS to which of the following organs? They're called clotting factors. e. All of these are correct. Factor V Leiden is an abnormal form of Factor V, it works perfectly in the clotting pathway and speeds up clotting as expected, but it cannot be turned off easily. You can view a list of our postings related to these issues at http://www.clotcare.com/clotcare/postings.aspx?by=condition&conditionid=6&word=Blood%20Clots. Abnormal bleeding after having a surgery. Factor V, coded for by the F5 gene, is a coagulation protein mainly synthesized in the liver. One other serious complication of Factor V deficiency or Owrens disease is hemorrhage or excessive bleeding both inside and outside the body. Obstetrics & Gynecology, Good Foods. Will the blood clot in my leg go away now that I am on medication for it? -Deep vein thrombosis If you have factor V Leiden and have developed blood clots, anticoagulant medications can lessen your risk of developing additional blood clots and help you avoid potentially serious complications. They're called clotting factors. The treatment involves exposing the infant's skin to fluorescent light at 420 nm to 470 nm wavelengths. Having venous thrombosis in unusual sites in the body such as the brain or the liver. This article on Epainassist.com has been reviewed by a medical professional, as well as checked for facts, to assure the readers the best possible accuracy. Within this cascade, many factors are present and integral to the process, and they are referred to as factor plus a Roman numeral (e.g., factor V and factor VIII). -Hematopoiesis WebIn the human body, factor V is a protein that is necessary for proper blood clotting. The clotting action of Factor V is controlled by another protein called Activated Protein C. To stop blood from forming clots, Activated Protein C easily turns off Factor V. Activated Protein C does not work as well on the abnormal Factor V Leiden protein. Some people have a genetic mutation of the protein which is called factor V Leiden. Your doctor may suspect factor V Leiden if you've had one or more episodes of abnormal blood clotting or if you have a strong family history of abnormal blood clots. There are numerous diseases that only affect the human blood. -Administration of a platelet transfusion, if deemed necessary. What measures are in place to protect my privacy? Having a DVT or PE during or right after pregnancy. 2018;43 (5) (Specialty&Oncology suppl):12-15. http://www.clotcare.com/clotcare/faq_postthromboticsyndrome.aspx, What are graduated compression stockings, where do I get them, and how do I put them on? -Platelet aggregation WebFactor V Leiden testing is not routinely recommended in the following situations: for the general population. US Pharm. The nurse is reviewing modifiable risk factors with the patient to avoid the redevelopment of thromboembolic complications, possibly leading to a second MI. Your doctor can confirm that you have factor V Leiden with a blood test. Factor V Leiden is caused by a faulty gene that you inherit from one or both parents. "When I received the call the night David passed away (April 5, 2003), I was clearly in a deep state of shock. 3. The clotting action of Factor V is controlled by another protein called Activated Protein C. To stop blood from forming clots, Activated Protein C easily turns off Factor V. Activated Protein C does not work as well on the abnormal Factor V Leiden protein. The practitioner is examining a client and notes that he has small, punctate skin hemorrhages on his abdomen and chest. Word: FACTOR V LEIDEN is engraved on the front just right of the medical emblem. Melanie also learned that David had a silent risk factor, Factor V Leiden - an inherited blood coagulant disorder that can increase a person's risk of DVT. If you have been diagnosed with Factor V Leiden, you should alter your diet to prevent excessive blood clotting. The mother also states that he was eager to walk but has now regressed and cries when she tries to encourage it. They estimate that the number of women with coronary disease needed to screen to prevent one episode of venous thromboembolism is 374. . Avoid pain medication. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The two most common hematological diseases the impairment of Factor V causes are Factor V deficiency or Owrens disease, and Factor V Leiden. Acquired Factor V deficiency or Owrens disease is caused by either by an underlying medical condition, certain medical drugs, or by an autoimmune reaction. WebWhat should you avoid with factor V Leiden? But in people who do, these abnormal clots can lead to long-term Manage Settings It is estimated that the risk of VTE increases 3 to 5 times in individuals using second-generation COCs and up to 6 to 8 times in those using third-generation COCs. Posted May 16, 2017 by Rachael 1000. -Oral contraceptives What also needs to be said about Factor V deficiency or Owrens disease is that it is a genetic disorder that is inherited in an autosomal recessive way. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. Medical conditions that might be a ground for the development of acquired Factor V deficiency or Owrens disease are the following: People who were treated with certain types of fibrin glue can also get this disorder. Importantly, Melanie also learned that DVT can be prevented if you are aware of the risk factors, signs and symptoms - and speak to your doctor. It is a medical condition that is known to cause small blood clots and also excessive bleeding, which happens due to overly active clotting proteins. Homemade cooking that is abundant in blood-building foods is the best home remedy for treating Factor V deficiency or Owrens disease. Factor V Leiden is the most common one. Talk to your healthcare provider to receive advice tailored to your needs. Does my factor V Leiden need to be treated? If you have factor V Leiden, you inherited either one copy or, rarely, two copies of the defective gene. Since vitamin K1 is so abundant in leafy green vegetables, most people dont need to worry about becoming deficient or taking a supplement. People who have certain autoimmune diseases, such as lupus, are also at a risk of developing Factor V deficiency or Owrens disease. Thrombogenic mutations are genetic, which should be considered in patients with a first-degree relative who has had VTE. WebMedicines help treat and prevent blood clots in people who are high risk for them. Do you have any brochures or other printed material that I can take with me? Talk to your healthcare provider to receive advice tailored to your needs. The possible need to wear compression stockings during long flights and road trips. WebSometimes people with the Factor V Leiden mutation may need to go on blood thinning medication to reduce the risk of developing blood clots. Since her husband's passing, Melanie has received over 80,000 letters and emails of support, including those from people who said his story saved their life. I had never before heard of this condition . People have a hard time whenever they hear they have a certain illness. WebYes, those living with factor v Leiden should avoid any foods that contain a high level of vitamin K. (Green leafy vegetables are a big one). The client comes to the emergency department with sudden onset of dizziness. Population that has Factor V Leiden is at a very high risk of developing giant and abnormal blood clots that can lead to stroke or heart attack. This people only have to eat foods that build blood and to avoid accidents, in which they could lose a lot of blood. It increases the chances that your blood will form abnormal blood clots that can be dangerous. WebSymptoms of Factor V Leiden include: Having a first DVT (deep vein thrombosis) or PE (pulmonary embolism) before 50 years of age. WebCancer Patients: Active Cancer in the Body: 20-25 grams of systemic enzymes per day 80 caps daily. Other methods of preventing pregnancy include barrier methods such as condoms (male and female), diaphragms, and cervical caps. That very day, David and the troops were going to face the most dangerous mission thus far by making the push across the Baghdad border. WebSymptoms of Factor V Leiden include: Having a first DVT (deep vein thrombosis) or PE (pulmonary embolism) before 50 years of age. Other risks Having Factor V Leiden does not appear to increase the chances of developing a heart attack or stroke. WebFactor V is one of the proteins needed to make blood form clots. Doctors generally prescribe blood-thinning medications to treat people who develop abnormal blood clots. WebYour treatment may include a medicine (called a blood thinner) that prevents blood clots. Although most patients are willing to accept some level of risk with contraception in return for the benefit of avoiding unplanned pregnancy, it is important to consider VTE risk when initiating contraception. If your factor V Leiden requires you to take anticoagulant medication, here are some steps that might help you prevent injury and avoid excessive bleeding: Avoid playing contact sports or engaging in other activities that could result in physical injury. Melanie learned of a Coalition - The Coalition to Prevent DVT - which is dedicated to this mission and she agreed to partner with them to become their national spokesperson. Factor V, coded for by the F5 gene, is a coagulation protein mainly synthesized in the liver. 12 Disorders of Hemostasis, Julie S Snyder, Linda Lilley, Shelly Collins, Exercise Physiology: Theory and Application to Fitness and Performance, Edward Howley, John Quindry, Scott Powers, Real Estate Preparation Chapters 11-15 (inclu. ; Disseminated intravascular coagulation (DIC) also causes Factor V deficiency or Owrens disease. Avoid dehydration. http://www.clotcare.com/clotcare/dvt.aspx, Cancer and Deep Vein Thrombosis About 1 of every 250 Black people in America has the prothrombin gene mutation. -Vitamin K WebHaving 1 Factor V Leiden gene (heterozygous type) slightly increases the chance of developing a blood clot. 2. Learn more at: -Bleeding Women who had difficult childbirth, in which they had lost a lot of blood are also at a risk of getting this hematological illness. The best way to cope with this disease is to talk about it with family and friends. - "I must stop breast-feeding my baby because of the anemia." The physician explains to her that her past medical includes an inherited defect in factor V Leiden, which predisposes her to the development of which of the following? Introduction: The incidence of factor V Leiden is documented to be around 5% in Caucasian population and is a known risk factor for venous thromboembolism (VTE). -Hypercholesteremia Clots can form in the veins near your bones that carry a lot of blood (deep veins), a condition called deep vein thrombosis. Effect of different progestagens in low estrogen oral contraceptives on venous thromboembolic disease: World Health Organization Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception. Some clots do no damage and disappear on their own. ; Disseminated intravascular coagulation (DIC) also causes Factor V deficiency or Owrens disease. -Deficiency of glucose-6-phosphate dehydrogenase (G6PD) The factor V Leiden mutation was found in 17% of venous thromboembolism cases and 6% of controls yielding an odds ratio of 3.3. WebSince Factor V Leiden is an inherited condition, there is no way to prevent it. Avoidance of alcoholic beverages during long flights. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs.
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